The three-day tour match will be the visitors' only chance for match practice ahead of the first Test of two against West Indies, starting next Saturday at the same venue.
"It's going to be an exciting tour, and I'm looking forward to it," said Mahela Jayawardene on arrival in Guyana.
"We've got some youngsters coming through the set-up now so it's going to be a very good experience for those guys and West Indies is a very good side so we're definitely looking forward to the challenge."
Jayawardene indicated that the key objective for his side is to win their first Test series in the Caribbean.
"We're very good at home," he said.
"In our conditions, we dominate, but away from home we've been winning a lot (recently).
"We beat England in England, New Zealand and we came close in Australia, so we're headed in the right direction, if we can keep competing away from home, challenging ourselves to be better cricketers every day that's the way forward.
"It's going to be a gr