A report released by Berlin-based Transparency International said many agencies need their government's consent to investigate suspected graft cases, while others face massive political interference during their probes.
"The region is characterised by a vicious cycle in which a highly elitist and unaccountable political culture remains largely unchallenged because the very actors who can bring those in power to task are being systematically silenced," said Transparency International Asia-Pacific director Srirak Plipat.
The report comes days after India's Congress party, embroiled in a string of corruption scandals during its 10 years in power, was thrown out of office in national elections.
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The study, released in Nepal's capital Kathmandu, examines efforts to fight graft in six South Asian countries -- Bangladesh, India, the Maldives, Nepal, Pakistan and Sri Lanka.
"As long as nobody brings the corrupt to justice, South Asia's leaders run the risk that future growth only benefits the p